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![]() This story was updated on May 9 with a statement from Toast. 650 Route 112, Port Jefferson Station, NY 11776 (opens in a new tab) (631) 331-6860. Spokespeople for Alexandria and Samuels did not respond to requests for comment. into a lab - a project that’s in part subsidizing a proposed 115-unit housing development behind the Trinity Orthodox Cathedral nearby. Samuels is also proposing to convert the site of the existing Star Market at 1400 Boylston St. That lab will eventually be home to a new Star Market grocery store. ![]() That deal kept Boston-based development firm Samuels & Associates on as a minority owner and manager of the property.Īlexandria and Samuels are also building a lab at 421 Park, the former Bed Bath & Beyond location situated between 401 Park and the MBTA Green Line Fenway station. The California-based life-science real estate development firm bought 401 Park in early 2021 for more than $1.5 billion in a bid to convert the building into lab-ready space. Several tech companies, in particular, have pared back space requirements amid a widespread shift toward more hybrid and remote work, while new leasing has slowed sharply from prepandemic levels.Īlexandria, meanwhile, has been rapidly growing its footprint in Boston’s Fenway neighborhood. Simple Breakfast Breakfast Croissant Country Fried Steak Steak and Eggs Ribeye Chilaquiles Biscuits & Gravy Brunch Burger Chimichurri Steak Breakfast. Toast is the latest company to downsize in Boston’s office market, which is enduring its highest vacancy rate in two decades. The shares have gained 7 percent so far this year. Burgers Avg 4.4 (2221 restaurants) From crispy smashed patties to reimagined classics and beyond. Brewpubs & Breweries Avg 4.4 (1166 restaurants) Team IPA or pilsner Whatever your style, find freshly poured pints here. Shares of Toast, which will report first-quarter earnings on Tuesday, climbed 5 percent on Monday after the lease termination filing. Fish, shellfish, and crustacean favorites from the sea, prepped the way you like. Toast employed 4,500 people worldwide at the end of 2022. But since 2019, it has been scaling back its presence. Toast moved to 401 Park - a massive art deco Sears building that has been converted to office and retail space - in 2015, and expanded its office footprint in the building four times before the COVID-19 pandemic hit. “As you can imagine, Toasters have lots of opinions about where we should go.” ![]() “We’re currently in the process of identifying our new location,” a spokeswoman for the company said in an e-mail. Add Chantilly cream for $2.In a statement to the Globe, Toast said it was looking for new office space in the area. Add blueberries or chocolate chips for $2. Served with your choice of daily soup, house greens, or roasted potatoes.Ģ fluffy buttermilk pancakes served with fresh berries, real maple syrup and your choice of smoked bacon or apple sage sausage. Our house made bacon cheddar jalapeno cornbread topped with caramelized onions, 2 poached eggs, and finished with roasted red pepper sauce. Choice of daily soup, house greens or roasted potatoes. Served on B&B’s Italian bread with hollandaise. Their Chopped Salad is so incredible, I dream about it. Breakfast potatoes grilled with nopales, tomatoes, cilantro, jalapeños, topped with carnitas, 2 eggs, crema & diced avocado served with tortillas or toast 13. served with breakfast potatoes, 2 eggs & toast 13.99 Carnitas Skillet. ![]() Your choice of peameal or spinach and mushrooms in garlic butter. Delivery & Pickup Options - 1888 reviews of Toast Bakery Cafe 'Toast has the ABSOLUTE BEST salad I have ever had in my life. Crispy house battered beef, covered in homemade sausage gravy. Scrambled tofu served with black beans, roasted tomato salsa, lime crema, roasted potatoes, and apple cider vinaigrette dressed greens. Sub tofu scramble for eggs to make it vegan. 2 eggs served with your choice of smoked bacon, apple sage sausage or roasted tomatoes, toast and roasted potatoes. ![]() ![]() ![]() For example, click Data and you’ll see options for creating Mac Only, Mac & PC, DVD-ROM (UDF), ISO 9660, and Photo Discs. Click the appropriate tab and you’ll find options for performing jobs that make sense for that category of tasks. Roxio has made Toast more intuitive by organizing tasks into tabs-Data, Audio, Video, Copy, and Convert. But that wasn’t true for the first few iterations of Toast 10 Titanium.Ī long-standing criticism of Toast is that while it’s crammed full of features, some of those features are difficult to ferret out. For the most part these features work as advertised-now. Toast 10 specifically adds the ability to extract clips from unprotected DVDs, save and convert Web-based Flash video, archive AVCHD files from an HD camcorder, convert audiobook CDs for iTunes or iPod playback, transfer video to a TiVo DVR, and capture and tag audio from external sources. Toast is also a tool for converting media creating disc images extracting video from media, devices, and the Web and streaming content over the Internet. Toast 10 Titanium does far more than just burn discs (for those interesting in upgrading from earlier versions, be sure to visit Roxio’s When you want to burn such discs, the time-tested advice you’re most likely to hear is “turn to Toast.” Yet Apple has shied away from supporting certain disc formats-Video CDs, music DVDs, and, most recently, Blu-ray, for example. The Mac has long been capable of burning CDs and DVDs-both data and media discs. ![]() ![]() ![]() With “people first” and “continuous innovation” staying at the core of its business philosophy, MicroPort® continues to provide innovative medical devices and integrated solutions to patients and physicians around the world. The unique soft-tip design makes the balloon catheter tip more pliable, and advanced laser welding technology realizes seamless connection between the tip and the body of the catheter to provide additional solutions for complex lesion treatment. nosis: a morphometric and quantitative evaluation by intravascular ultra. ![]() Made of internationally advanced materials, the ultra-long hydrophilic coating significantly improves the crossing and pushing of catheters. The OPN NC super high-pressure balloon (SIS Medical AG) is a rapid exchange percutaneous transluminal coronary angioplasty. compliant balloon angioplasty for long and calcified infrapopliteal and. MicroPort® Foxtrot® Pro PTCA Balloon Catheter is also suitable for lesion dilation before stent implantation in PTCA procedures. The approval of Firefighter™ and Foxtrot® Pro has expanded the coronary product offerings of MicroPort® in Pakistan and enables local patients access to a wider range of treatment solutions. Case Study: Aneurysm Coiling AVM Embolization Balloon Occlusion Test Balloon Occlusion Test Procedure Information Carotid Angioplasty/Stenting Cerebral. (MicroPort®) has recently received registration approval from the Drug Regulatory Authority of Pakistan for its Firefighter™ PTCA Balloon Catheter (Firefighter™) and Foxtrot® Pro PTCA Balloon Catheter (Foxtrot® Pro) products.įirefighter™ is made of flexible materials and its outer diameter allows extremely small balloons to pass through, so that two balloon catheters can be contained within a 5F guiding catheter, making it easier for physicians to perform complex operations, such as docking.ĭesigned for coronary dilation through percutaneous transluminal coronary angioplasty (PTCA), MicroPort® Firefighter™ PTCA Balloon Catheter can be used with the company’s Firehawk® Rapamycin Target Eluting Coronary Stent System for lesion dilation before stent implantation. It is strictly forbidden to make copies, whether partial or total and on whichever media without prior approval.Islamabad, Pakistan – Shanghai MicroPort Medical (Group) Co., Ltd. This Website is protected by the laws on copyright and by the relevant international conventions. It is a standard treatment for narrowed or blocked arteries in this area of the body. Prior to use, please consult device labeling for prescriptive information and operating instructions. Angioplasty is a medical procedure that opens up a blocked or narrowed artery around the heart. The Sanderum Centre, 30a Upper High Street, Thame. ![]() To the extent this site contains information, reference guides and databases intended for use by licensed medical professionals, such materials are not intended to offer professional medical advice. AlveoHP is an ultra-low profile, high pressure PTCA balloon ideal. Please note that the following pages are exclusively reserved for health care professionals in countries with applicable health authority product registrations. For health care professionals in EUROPE excepted those practicing in France as the following pages are intended to all International health care professionals and are not in compliance with the French Advertising law N☂011-2012 dated 29th December 2011 article 34. Other health care professionals should select their country in the top right corner of the website. ![]() ![]() ![]() snoozing events will be much easier)Updated that experimental time picker ctrl on the edit event form (it will be more usable)Fixed a bug where if you were using 24hr clock you couldn’t set an event time for 12amAdded a system wide hot key (Ctrl + Shift + E) which allows you to create an event using selected text in any other application (useful to create new events from emails or web pages etc)Configurable notify window transparencyYou can now execute an application with an event without showing a pop-up (optional)Added functionallity to create scripts to execute directly within Event Manager (no more hunting for lost batch files)Added functionallity to create any type of script to execute (e.g.bat. ![]() On the next window, scroll down, and under Exclusions, click on Add or remove exclusions. ![]() Next, go to Virus & threat protection settings and click on Manage settings. On the Windows Security page, click on Virus & threat protection. Keep your events safe with auto backupsImproved GUI (minor changes to the look)Changed the look of the notify window and how it works (e.g. Expand the system tray on the taskbar and click on the Windows Security icon. py, ps1 anything you like)Added incremental search on the event and category columns Changes Keep your events safe with auto backupsImproved GUI (minor changes to the look)Changed the look of the notify window and how it works (e.g. Users of EPSON Event Manager gave it a rating of 4 out of 5 stars.Keep track of important dates in your personal and professional life The most prevalent version is 3.11.53, which is used by 19 % of all installations.ĮPSON Event Manager runs on the following operating systems: Windows/Mac/Linux. It was initially added to our database on. The latest version of EPSON Event Manager is 3.11.53, released on. Wenn Sie whrend oder nach der Installation der Epson Software auf die Taste Keep Blocking (Weiter blockieren) im Fenster Windows Security Alert (Windows-Sicherheitsalarm) geklickt haben, geben Sie den Epson Event Manager frei. It was checked for updates 22,431 times by the users of our client application UpdateStar during the last month. Epson Event Manager Stellen Sie sicher, dass Epson Scan und Epson Event Manager ordnungsgem installiert sind. ![]() OverviewĮPSON Event Manager is a Shareware software in the category Business developed by EPSON Event Manager. It makes scanning users projects even quicker. It listens to events that have triggered the scanner function of EPSON printers and all-in-one devices.ĮPSON Event Manager also allows users to assign any of the product buttons to open a scanning program. The application can be accessed from the system tray. It is used to provide support to different EPSON scanners and does things like facilitate Scan to Email, Scan as PDF, Scan to PC and other uses. Epson Event Manager Utility assists you to take advantage of the main features of an Epson product. ![]() ![]() ![]() Works on both oil and water-based stains and spots. Comes with a convenient fatigue free trigger sprayer that works on grease, tar, pet stains, soda stains and dozens of others. Lifts coffee, grease, pet stains & dozens more. BlueMagic Carpet and Stain Spot Lifter is the number 1 selling spot lifter in the category in the automotive chain stores. The one-step stain & spot remover for home and auto. UPC 077336900120 is associated with product Blue Magic 900 Carpet Stain & Spot Lifter - 22 oz. Note: manufacturer's liability is limited to the replacement of product or refund of purchase price.īlue Magic and products that perform are registered trademarks of Blue Magic, Inc.īlue Magic® Carpet Stain & Spot Lifter. Simply return unused portion to Blue Magic® with proof of purchase. Guarantee: Money back guarantee when used as directed. Some common uses include: Grease, tar, blood, wine, urine, coffee and hundreds more. Find quality automotive products to add to your Shopping List or order online. Works on both oil and water-based stains and spots. Shop for Blue Magic Carpet Stain & Spot Lifter (22 Oz) at Frys Food Stores. Find quality automotive products to add to your Shopping List or order online for. The one-step stain & spot remover for home and auto. Shop for Blue Magic Carpet Stain & Spot Lifter (22 Oz) at Food 4 Less. Lifts coffee, grease, pet stains & dozens more. ![]() Spray area thoroughly, wait 10 to 15 seconds and blot firmly with a clean dry towel or absorbent cloth. Shop for Blue Magic Carpet Stain & Spot Lifter (22 Oz) at King Soopers. Remove loose dirt or blot excess liquid with a clean towel or absorbent cloth. spray can of Blue Magic carpet stain and spot lifter is perfect for auto carpets. Note: Some very tough older spots and stains may require gentle brushing with a soft bristle brush.ģ. Blue Magic 900 Carpet Stain and Spot Lifter 22 oz. Spray stained area thoroughly, allow 30 seconds, blot stain firmly with clean dry towel or absorbent material, repeat as needed to clean tough older spots and spots. ![]() ![]() ![]() I do not check this site often and found I could not reply, and there was no email on your profile, so I am replying here: You had replied to a comment of mine asking what I’d meant by “Google figured out hardware didn’t matter on the server” by 2000 and how that changed the internet to make Bill’s vision come true. ![]() ― Tracy Kidder, The Soul of a New Machine. “In a book called Computer Power and Human Reason, a professor of computer science at MIT named Joseph Weizenbaum writes of a malady he calls “the compulsion to program.” He describes the afflicted as “bright young men of disheveled appearance, often with sunken, glowing eyes,” who play out “megalomaniacal fantasies of omnipotence” at computer consoles they sit at their machines, he writes, “their arms tensed and waiting to fire their fingers, already poised to strike, at the buttons and keys on which their attention seems to be as riveted as a gambler’s on the rolling dice.” Other than this one programmer, I’ve never seen any programmers or product managers or engineers as attractive as in this show. She was doing well as a programmer when the company folded. She was really pretty, prettier than the actors on Halt and Catch Fire, and got a ton of attention from the rest of the programmers who were almost all typical programmers. She was also an ex model from Denmark or Belgium or somewhere. I worked for a startup and we had a programming intern in my shop who was a new mom who wanted to learn programming. ![]() ![]() ![]() ![]() Even when current treatment options are applied, these disorders often progress, reflecting the inadequacy of currently available medications for many patients. Major depressive disorder and substance use disorder are widespread and are associated with a tremendous cost in terms of family disruption, lost productivity and medical care. We study this question in a mouse model (electrophysiological recordings, protein assays), in which injection of lipopolysaccharide induces the key electrophysiological signatures of delirium (increased slow wave activity even during wakefulness, altered cortico-cortical connectivity) in order to identify the signaling pathways linking inflammation to changes in brain function. We know that inflammation is the predominant acute cause of delirium, but how inflammation induces such a drastic shift in cognition remains unclear. It is a condition that is associated with substantially increased mortality, prolonged hospital stays, and long-term cognitive deficits, but is bereft of therapeutic interventions. Delirium is an acute disorder of consciousness involving reduced attention, disorganized thinking, and fluctuating arousal levels that often affects sick elderly patients and especially those undergoing high risk surgeries. In addition, we investigate how these changes under anesthesia overlap with those observed during natural sleep in an effort to identify the neural correlates of loss and recovery of consciousness. We use rodent models (in vivo and brain slice preparations patch clamp and multi-channel electrophysiological recordings calcium imaging) as well as human subjects (intracranial electrophysiological recordings from neurosurgical patients structural and functional MRI computational models) to explore the effect of anesthetic agents on signal processing (auditory, visual) and connectivity (single cell network) and relate those effects to changes in arousal. Rather, anesthetics disrupt the integrative processes of the brain through a complex set of molecular, cellular, circuit and global effects. We have shown that anesthetics do not just turn the brain off, nor are changes in information content of brain activity related simply to changes in arousal state. Despite being in widespread use since the mid-19th century and administered to 20 million patients annually in the US alone, how anesthetics cause loss of consciousness remains one of the great open problems in biomedical science. Our areas of interest include mechanisms of loss and recovery of consciousness under anesthesia, the overlap of these mechanisms with changes in arousal during natural sleep, the link between inflammation and brain function during delirium, and the mechanisms whereby psychedelics ameliorate psychiatric disorders (depression, substance use disorder). We study this question in human subjects and rodent models using behavioral assays as well as imaging and electrophysiological measurements focused primarily in neocortex and thalamus. Research in my lab centers on how changes in brain activity and connectivity result in changes in consciousness. ![]() ![]() ![]() I’m just making broad general statements with little understanding of your real medical situation. Take all advice from your personal doctor. ![]() To see MBBB suggests severe underlying conduction system disease, often associated with a poor prognosis (Nice review by Dhanse on this subject here. That’s when you regret not pumping that blood through that heart at age 42 with some exercise. MBBB (Masquerading Bundle Branch Block) is a rare but important finding on ECG in which the chest leads show a RBBB-like pattern and the limb leads resemble LBBB. That’s probably not angina you have at age 42. When someone has heart block, it means their heart can beat slowly or miss beats. It’s also it’s own risk factor for separate events all together. Heart block is a type of arrhythmia, which means irregular or abnormal heartbeat. It’s kind of an ‘accelerant’ for underlying cholesterol and gunk to form faster and burst faster. Hypertension is a separate risk factor for that calcium or plaque rupturing in the future. That being said sometimes we repeat the score in 3-5 years depending on whether any real worthwhile changes were even done in order to re-enforce continuation of those positive habits.Ĭontrolling hypertension is likely helping sure. These buy you the best chance of reversing, halting, or reducing acceleration of more calcium or plaque formation. There’s no way around not doing those things. Repeating it won’t do you much good except remind you about what you already know especially if you haven’t lost weight, started eating cleaner, and started exercising. Typical RBBB shows wide S-wave in the lateral lead 1 and aVL, while atypical RBBB pattern lacks S-wave in lead 1 and aVL, and coexisting left-axis deviation, and may be associated with coexisting PR prolongation due to delayed activation over the left bundle. ![]() Thus, your risk of cardiac events slowly goes up every year. An atypical RBBB may identify possible CRT responders. On average these scores tend to increase by a certain percentage each year after the test if your lifestyle stays the same. I’m just worried about exercise because I fear angina that i think I had once but it went away so fast (split second) when I stopped running that I thought it might have been gas or something unrelated.Ĩ3 is not that high at all, but it tells you that a negative process has begun. I have a 49 inch waist and am really taking my health seriously this year.Īt my Cardiology appointment, MD didn’t seem to be too concerned saying they treat at 400 but I’ve read my 95 percentile should be really worrisome.Ģ) is it possible that me being on meds for HTN and Gout maybe is helping slow this? I’m about 5’10 250 pounds with all my weight in my stomach. I also had high Uric Acid I’ve been treating with Allopurinol for the last 3 years as well. I had untreated hypertension that I’ve been taking Lisinopril and Metoprolol for. So since it was my initial test there is no telling how long I’ve been laying down plaque or If it’s been accelerating just recently. In 1,224 white men with normal QRS morphologies and frontal axis (-25 to 100), the 98% upper and lower bounds of QRSD with the 12SL algorithm, like that seen in BSMs, was 80-116 ms, peak 96 ms.At 42 about a year ago I took a calcium score and got a score of 83 which put me in the 95 percentile in my group. It sometimes makes it harder for the heart to pump blood to the rest of the body. LBBB and RBBB were identified according to standard definitions (QRS duration > 120 ms). Bundle branch block is a condition in which there's a delay or blockage along the pathway that electrical impulses travel to make the heart beat. Sixty-three (5%) had a QRSD greater than or equal to 112 and less than or equal to 116 ms-36 of this group had normal morphology 1 had typical RBBB and 26 had R' V1, V2 (considered a normal variant as it occurred in 360 of 1,164 remaining with QRSD less than or equal to 108). The present study categorized QRS duration as narrow ( 100 ms) or prolonged (> 100 ms), with prolongation further classified into LBBB, right bundle branch block (RBBB) and intraventricular conduction delay (IVCD). Twenty-seven of 1,254 (2.1%) had QRSD greater than or equal to 120 ms-14 of these had normal morphology 2 had RBB 3 had atypical RBB 5 had R' in V1, V2 2 had WPW and 1 had Superior Fascicular Block. The frontal QRS axis was between -30 and -65 in 22 of 1,254 (1.8%). All had a negative history (including drugs known to affect the cardiovascular or pulmonary systems), a negative family history (in immediate family members before age 55), no physical findings suggestive of heart disease, a normal blood chemistry profile, pulmonary function tests, and symptom limited bicycle exercise test. These include blood clots to the lung (pulmonary embolus), chronic lung disease, cardiomyopathy, and atrial and ventricular septal defects. The QRS duration (QRSD) on a digital 12 simultaneous lead ECG was measured by a commercially available recording cart (Marquette MACII 12SL) in 1,254 white male safety workers (ages 19-65, mean 34). RBBB occurs in medical conditions that affect the right side of the heart or the lungs, so a finding of RBBB on the ECG ought to trigger a screening exam for such conditions. ![]() ![]() How does benefit-cost analysis fit into the project development process?Ī benefit-cost analysis is a tool for assisting project managers when they are evaluating and comparing different alternatives. A benefit-cost analysis provides monetary measure of the relative economic desirability of project alternatives, but decision-makers often weigh the results against other non-monetized effects and impacts of the project. A properly conducted benefit-cost analysis would indicate whether travel time and safety savings exceed the costs of design, construction, and the long-term increased operating costs.īenefit-cost analyses have been used as a tool by project managers to help evaluate preliminary concepts during early planning studies, to evaluate alternatives and select a Preferred Alternative as part of project environmental documentation, and to evaluate potential design and construction staging options as part of detailed design and/or construction. For some kinds of projects, such as bypasses, travel times and safety may improve, but operating costs may increase due to longer travel distances. The primary transportation-related elements that can be monetized are travel time costs, vehicle operating costs, safety costs, ongoing maintenance costs, and remaining capital value (a combination of capital expenditure and salvage value). The objective of a benefit-cost analysis is to translate the effects of an investment into monetary terms and to account for the fact that benefits generally accrue over a long period of time while capital costs are incurred primarily in the initial years. In other words, a benefit-cost analysis tries to answer the question: What additional benefits will result if this Alternative is undertaken, and what additional costs are needed to bring it about? ![]() The analysis evaluates incremental differences between the Base Case and the Alternative(s). Typically, a “Base Case” is compared to one or more Alternatives (which have some significant improvement compared to the Base Case). Section 5 Conducting a Benefit-Cost AnalysisĪ benefit-cost analysis is a systematic evaluation of the economic advantages (benefits) and disadvantages (costs) of a set of investment alternatives.Section 4 Economic Terms and Principles. ![]() Section 3 How Does Benefit-Cost Analysis fit into the Project Development Process?.Section 2 What is Benefit-Cost Analysis?.This document presents benefit-cost analysis guidance for highway improvement projects in the following sequence: This Guidance is based on “User Benefit Analysis for Highways”, AASHTO, August 2003. Review of relevant stages in conducting a benefit-cost analysis for highway projects.Discussion of economic terms and principles.Background information on benefit-cost analysis and how it may fit into the project development process. ![]() This document is intended to provide guidance to perform benefit-cost analysis for highway projects. Benefit-Cost Analysis for Transportation Projects 1. ![]() |